Tumor tissues obtained from tumor-bearing CD11c:DTA mice exhibited higher transcriptional expressions of IL-10, transforming growth factor (TGF)-β, indoleamine 2,3-dioxygenase (IDO), vascular endothelial growth factor (VEGF), arginase, inducible nitric oxide synthase (iNOS), cyclooxygenase (COX)-2, and membrane-associated prostaglandin E2 synthase (mPGES) than tumor-bearing WT mice. The gene discussed is IDO2; the disease is neoplasm.