PTPRC and neoplasm: When compared with tumor-bearing WT mice, tumor-bearing CD11c:DTA mice exhibited the marked infiltrations of Gr-1+CD11b+F4/80− PMNs, Gr-1+CD11b+F4/80+ monocytes/macrophages, and B220+ B cells, whereas they displayed the significant reduction in the accumulations of CD11chi cDCs, CD11c+Siglec-H+ pDCs, and CD3+CD8+ T cells (Figures 1I–K).