CD8A and neoplasm: To determine the influence of the constitutive elimination of CD11chi DCs in the initiation of Ag-specific T-cell responses in tumor-bearing mice, eFluorTM 670-labeled OT-II CD4+ T cells or OT-I CD8+ T cells were adaptively i.t. or i.v. transferred into B16-OVA-bearing mice to determine their Ag-specific division in tumor tissues or TdLNs and Spl, respectively.