Induce caspase-mediated apoptosis in hepatocellular carcinoma cells, upregulate the expression of chemokines CCL2, CCL17, and CCL22, increase the expression of the main receptor for granzyme B in hepatocellular carcinoma tissue, the mannose-6-phosphate receptor (M6PR), and promote recruitment of CD8+ T cells to hepatocellular carcinoma tissue. Here, GZMB is linked to hepatocellular carcinoma.