Our immunohistochemistry results show that CRS protocol increases the number of Iba-1 positive cells/mm2 in the DG, while Treg cells peripheral administration into CRS mice significantly reduces it, observing lower values than in the controls (control 87.3 ± 6.9 vs. CRS 112.2 ± 17.9 vs. CRS + Treg cells 54.9 ± 19.1 n° of Iba-1+ cells/mm2; Cohen’s d size effect of 1.1 between control and CRS, 1.9 between CRS and CRS + Treg cells, and 1.33 between control and CRS + Treg cells) (Figures 4Ba–c,C). This evidence concerns the gene AIF1 and congenital rubella syndrome.