Fabry–Anderson or Fabry disease (FD, OMIM#301500) is a rare X-linked lysosomal storage disorder resulting from the absence or impaired function of α-galactosidase A (GLA, OMIM*300644), an enzyme responsible for the catabolism of glycosphingolipids by hydrolysis of the terminal α-galactosyl moieties from glycolipids and glycoproteins. This evidence concerns the gene GLA and Fabry disease.