CRLS1 and metabolic syndrome: ACACA,acetyl-CoA carboxylase alpha, is a fatty acid biosynthesis gene andis also shown to be upregulated in low-fat diet-fed mice after TPHPexposure.46 PLIN2, or perilipin 2, is anadipogenesis gene crucial for lipid storage that might impair lipiddroplet formation and mobilization, contributing to conditions suchas insulin resistance and metabolic syndrome.47 CRLS1 is a cardiolipin synthesis gene and a phospholipid of themitochondrial membrane and plays an important role in mitochondrialfunction and numerous cellular processes, including cardiovascularhealth.