Jin et al. showed that in microglia, PQBP1 recognizes extrinsic tau protein, which has been associated with several neurodegenerative disorders including AD, frontotemporal dementia with parkinsonism-17 (FTDP-17), Pick disease (PiD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) [91]. This evidence concerns the gene PQBP1 and supranuclear palsy, progressive, 1.