Finally, although these features have not been studied extensively, TRIM18/MID1 has been shown to alter T-cell motility in an mTOR-dependent manner [90,91], leading to accrued inflammation following experimental infections [89,92], and to influence the exocytosis of lytic granules from cytotoxic T cells along with TRIM1/MID2 [93,94]. This evidence concerns the gene MID1 and infection.