Moreover, a significant reduction of 75% in survivin protein relative levels was observed in total protein extracts from SKOV3 (Figure 7D,F), as was previously described in CrFK cells (Figure 7C) [4], indicating that the expression of the LC protein also causes a reduction in the survivin levels in an ovarian cancer cell line that overexpresses survivin. This evidence concerns the gene BIRC5 and ovarian carcinoma.