Proteomic studies by Nkosi et al. showed that LMP-1 has the ability to modify the cargo of sEV secreted from infected B lymphocytes, increasing the content of proteins involved in EBV infection, endocytosis, apoptosis, and the MAPK and NF-Kb signaling pathways, as well as adhesion molecules [93]. The gene discussed is PDLIM7; the disease is Epstein-Barr virus infection.