NLRP3 and infection: In detail, MwS extracts recorded a strong inhibition of infection in co-treatment (Figure 4A): MwS3 exhibited an IC50 at 9 μg/mL, MwS2 at 21 μg/mL, while, on the contrary, and similarly to what was observed with HCoV-229E, MwS1 did not show any antiviral effect.