The combined stress caused by viral infection and water deficiency led to significant expression of the genes StPR1, StPR3, StPR6, StPR9, and StPR10 in the variant with ChCA treatment; however, when using a mixture of ChCA + B. subtilis 47, the transcriptional activity of PR proteins was lower. This evidence concerns the gene TMEM37 and hyperinsulinemic hypoglycemia, familial, 4.