In the last decade, the antidepressant and anxiolytic-like effect of glitazones has been reported [106,107,108], and the expression of the inactive form of PPARγ in the amygdala was observed in response to CAF (an increase in 300% vs. control) at the same time as the increase in anxiety (reduction of 40% in the exploration of open arms in the plus-maze test) [7]. This evidence concerns the gene PPARG and Anxiety.