PRNP and scrapie: Hence, to characterise circulating goat scrapie strains, a vast collection of goat field scrapie isolates from all over Europe, which includes atypical scrapie as well as experimental caprine BSE (gtBSE) and CH1641, were inoculated in a panel of conventional (RIII) and transgenic mice overexpressing PrPC of different species (Tg110, Tg338, Tga20, Tgshp IX and Tg501) as well as bank voles.