Marked differences in the expression of fibroblast growth factor 2 (FGF-2) were found between the group of patients taking amlodipine who developed gingival enlargement compared to those not taking amlodipine but had gingival enlargement, as well as between the patients not taking amlodipine that had gingival enlargement and the patients taking amlodipine without gingival enlargement (Figure 3). The gene discussed is FGF2; the disease is gingival overgrowth.