NR1H3 and steatosis: In both MASLD and hepatitis C virus (HCV)-afflicted patients with steatosis, hepatic LXRα expression, alongside lipogenic (e.g., PPAR-γ, SREBP-1c, SREBP-2, and FAS) and inflammatory genes (e.g., TNF-α, IL-6, and iNOS), is abnormally increased, pointing to the conceivable role of LXRα in these liver conditions’ pathogenesis [84].