Oxyresveratrol achieves a variety of pharmacological activities by acting mainly on inflammation, tight junctions, and cancer pathways [144], the PI3K/AKT signaling pathway [145], insulin regulatory pathways, AD and other neurodegenerative disease pathways, lifespan regulatory pathways, etc. Oxyresveratrol’s effects on anti-intestinal inflammation, liver-injury treatment, and nervous system protection are closely related to the gut–liver–brain axis [146,147,148,149,150]. The gene discussed is AKT1; the disease is neurodegenerative disease.