HLA-A and bacterial infectious disease: The A2.DR1 mouse model, using HLA-A*02:01/Db for MHC-I and HLA-DR1 for MHC-II [39], proved to be a valuable tool for delineating HLA-restricted epitopes in both viral and bacterial diseases, and it has been instrumental in evaluating the T cell-specific immunogenicity of vaccines [52,53,54,55,56,57,58].