ACHE and amyloidosis: Fortunately, in addition to AChE inhibitor medications, studies have shown that curcumin therapy acts protectively in the pathogenesis of AD, reducing OS and inflammation, in addition to inhibiting the formation of Aβ fibrils from Aβ40 (1–40) and Aβ42(1–42) and amyloid plaques [170,171,172,173,174,175].