MAPT and Alzheimer disease: A mouse model of AD induced by scopolamine or Aβ1-42 treated with curcumin showed a significant decline in lipid peroxidation and increased superoxide dismutase levels, in addition to a reduction in Aβ aggregation and tau hyperphosphorylation through the regulation of GSK3β, Cdk5, p35, and p25 [184,185].