Previous studies could find higher values of ceramides with long fatty acyl chains, namely, Cer(d18:1/18:0), Cer(d18:1/20:0), and Cer(d18:1/24:1), in patients with obesity and type 2 diabetes mellitus [23]. The gene discussed is CBLN1; the disease is obesity due to melanocortin 4 receptor deficiency.