Using Cox multivariate proportional hazards analysis, after adjusting for potential confounders, in model 1, several parameters, such as SPPB (functional capacity), albumin (nutritional biochemical parameter), and CRP (inflammation parameter), and in model 2, factors such as SPPB, CRP and %IBW (like muscular parameter), were significantly associated with the risk of all-cause mortality in CKD patients. This evidence concerns the gene CRP and chronic kidney disease.