FTO and obesity due to melanocortin 4 receptor deficiency: For instance, dietary patterns that emphasize whole grains, vegetables, and fruits, and limit total and saturated fats, such as the Mediterranean and DASH diets, have demonstrated the potential to lower the risk of obesity for people with high genetic predisposition scores for obesity, especially in those with risk alleles of FTO rs9939609, rs1121980, and rs1421085 [29].