GPT and obesity due to melanocortin 4 receptor deficiency: Furthermore, children and adolescents with obesity had significantly increased markers of inflammation [white blood cell count, erythrocyte sedimentation rate (ESR), ferritin], ALT, γGT, uric acid, and T3 concentrations, as well as lower concentrations of total 25-OH-Vitamin D compared to subjects with overweight and normal BMI.