IL1B and metabolic dysfunction-associated steatotic liver disease: In addition, in one mouse model of MASLD, SB reduced hepatitis activity according to the NAS scale, production in the liver of TNF-α, IL-1β, interferon-γ, and IL-10 as well as the inflammatory cell chemoattractant CCL-2 and macrophage (Kupffer cells) biomarker F4/80 [29].