HLA-DRB1 and autoimmune disease: Around 15% of the patients with RPL have thyroid autoimmunity [128,129], and the HLA alleles associated with RPL patients are linked to autoimmune diseases: DRB1*1501 with multiple sclerosis, DRB1*07 with interstitial lung disease, and DQB1*05 with autoimmune encephalitis.