Examinations of gene expression in children residing in trachoma-endemic regions reveal a significant rise in the conjunctival expression of IFNγ and factors associated with TH1 cells, such as IL-12B and indoleamine-2,3-dioxygenase (IDO1), along with increased activity in NK cell pathways marked by NCR1, CD56, and CD247 [57,58,59]. This evidence concerns the gene IFNG and inclusion conjunctivitis.