In addition, Phellinus igniarius polysaccharide (SHPS-1), which has a 1,3-β-D-GLCP residue structure, can significantly reduce the phosphorylation of STAT-1 and the expression of STAT-1 target genes in LPS-stimulated RAW264.7 macrophages, as well as the release of iNOS and TNF-α, and can reduce the levels of inflammatory factors in mice with enteritis. Here, STAT1 is linked to enteritis.