In addition, in PPARγ knockout septic mice, the expression of NF-κB, Bax, and cleaved caspase-3 increased, while the apoptosis rate and Bcl-2 expression decreased in the livers of the mice, suggesting that PPARγ is involved in regulating the inflammatory response and apoptosis in sepsis-induced liver injury. This evidence concerns the gene PPARG and Sepsis.