Recently, another DDS for Resv was designed by Lin et al., who reported that Pep-1, a short peptide containing nine amino acids (CGEMG-WVRC), was able to bind to both subcutaneous and orthotopic GBM xenografts expressing IL-13Rα2, a 65 kD plasma membrane receptor, overexpressing in GBM tissues and able to mediate endocytosis after binding to its ligand. The gene discussed is IL13RA2; the disease is glioblastoma.