Berberine also enhances autophagy in glioblastoma by modulating the AMPK/mTOR/unc-51-like autophagy-activating kinase 1 (ULK1) pathway and inhibits the proliferation of human gastric cancer cells by deactivating the MAPK/mTOR/p70S6K/Akt signaling cascade both in vivo and in vitro. This evidence concerns the gene MTOR and glioblastoma.