TMTC1 (Transmembrane O-Mannosyltransferase Targeting Cadherins 1, 615855), as a specific gene signature in our rules for dilated cardiomyopathy identification, is shown to be associated with the risk of heart failure [66], which is a common symptom for such CHD subtype [67]. This evidence concerns the gene TMTC1 and dilated cardiomyopathy.