For dilated cardiomyopathy, XIST acts with IDI2-AS1 together to contribute to disease pathogenesis [111], while for hypertrophic cardiomyopathy, XIST acts with miR-330-3p [112,113], validating that different pathogenic mechanisms are involved even for the same genes across different congenital heart disease subtypes. Here, IDI2 is linked to congenital heart disease.