Endothelial cell-based prediction identified a series of different literature-supported gene signatures like COL25A1 (Collagen Type XXV Alpha 1 Chain, 610004) for dilated cardiomyopathy [71] and neo/HF-hypoplastic left heart syndrome [72], NFIB (Nuclear Factor I B, 600728) for hypertrophic cardiomyopathy [73], and KLF7 (Kruppel-Like Transcript Factor 7, 604865) for Tetralogy of Fallot [74]. The gene discussed is COL25A1; the disease is hypertrophic cardiomyopathy.