In logistic regression analysis, there was a significant positive correlation only between IL-6 and AF in both univariate logistic regression (OR 1.175; 95% CI 1.013–1.363; p = 0.034) and multivariate logistic regression analysis when accounting for NT-proBNP, hsCRP, IL-10, orosomucoid and endocan (OR 1.327; 95% CI 1.068–1.650; p = 0.011). The gene discussed is NPPB; the disease is atrial fibrillation.