This degradation influences cancer development by promoting cell proliferation, reducing apoptosis, and facilitating metastasis through pathways such as phosphatidylinositol-3 kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) and mitogen-activated protein kinases (Ras/Raf-MEK-MAPKs) [25,26,27,28]. The gene discussed is WNK2; the disease is cancer.