SLC5A2 and Hypoglycemia: As for AE, only two patients in the DMP groups presented AE; one of them was hypoglycemia (the patient was under hypoglycemic treatment with GLP-1ra and insulin), which was classified as a serious event, of moderate intensity, which required a reduction in insulin doses in addition to the suspension of SGLT-2 inhibitors (empagliflozin), resolving the condition.