LRBA and infection: Although, to date, the functional roles directed by ECAMs have not been studied to any great detail in mollusk‒parasite interactions, based on the findings reported here, it can be suggested that molecular alteration of either the Bgl-miR-let7-5p/Bgl-ECAM and/or Bgl-miR-2a-2-3p/ECAM expression module is initiated by B. glabrata as part of its early immune responses to infection by the S. mansoni parasite.