In conclusion, from our digenic network, we proposed that in the cerebral cortex, the variant of MYH9 might work as a modifier of SCN1A and, in this family, led to intra-family seizure phenotype variability, whereas in the bone marrow, the variant of MYH9 has probably led to thrombocytopenia. This evidence concerns the gene MYH9 and Thrombocytopenia.