Using the RNA-seq data of 100 leukemia/lymphoma cell lines, we screened the expression levels of TGFb-pathway members and detected strong activities of the TGFb-receptor gene TGFBR2 in BCP-ALL cell lines (Figure 6B), which may reflect the physiological significance of this pathway therein. The gene discussed is TGFB1; the disease is acute lymphoblastic leukemia.