Meningiomas often overexpress growth factor receptors, such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and epidermal growth factor (EGF); therefore, several studies using monoclonal antibodies or small-molecule kinase inhibitors have been conducted with limited or no success [147,152,153,154]. This evidence concerns the gene VEGFA and meningioma.