Neurofibromatosis type 2, now termed NF2-related schwannomatosis, caused by a mutation in the NF2 gene, results in the loss of function of Merlin, a tumor suppressor protein, which leads to the overexpression of YAP1 (yes-associated protein 1) [94,95,96]. This evidence concerns the gene YAP1 and NF2-related schwannomatosis.