The NT-proBNP levels were positively associated with atrial fibrillation (r = 0.36, p = 0.001), E/e′ (r = 0.34, p = 0.001), the LAVI (r = 0.31, p = 0.001), LVH (r = 0.27, p = 0.044), and age (r = 0.22, p = 0.048) and inversely correlated with GLS (r = −0.35, p = 0.001) and the eGFR (r = −0.32, p = 0.001). The gene discussed is NPPB; the disease is atrial fibrillation.