Our team focuses on the investigation of circulating biomarkers for predicting the severity of ALI/ARDS, such as Matrix Metalloproteinase-3 (MMP-3) [18], Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) [19], microvesicle-encapsulated microRNA-223 [17], and Club cell secretory protein (CC16) [20,21], which is also known as CC10 or uteroglobin. Here, MMP3 is linked to acute respiratory distress syndrome.