IGHE and allergic rhinitis: For the scope of this article, regarding the term AIT, we will refer to allergic rhinitis and allergic asthma treatment only; this therapy is offered to individuals who are affected by immunoglobulin E (IgE)-mediated allergic rhinitis and/or allergic asthma due to inhaled allergens, such as pollens, house dust mites (HDMs), molds, or pet danders.