LEP and Insulin resistance: Multivariable linear regression analyses indicated significant associations between HRI and WC (unstandardized regression coefficient (B)) = 0.02, 95% CI 0.00, 0.03), waist/hip ratio (B = 1.58, 95% CI 0.19, 2.98), AST (B = 0.02, 95% CI 0.00, 0.03), homeostatic model assessment for insulin resistance (HOMA-IR) (B = 0.03, 95% CI 0.005, 0.06), and Leptin (B = −0.003, 95% CI −0.005, 0.00), after correction for BMI-z-score (Table 3).