The results show that the combination of DEX and MCG can regulate the immune system process, receptor complex, immune receptor activity, etc. The KEGG results show that DEGs were significantly enriched in the Rap1 signaling pathway, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, MAPK signaling pathway, Th17 cell differentiation, etc., and the pathways (p < 0.05 and impact > 0.1) potentially associated with glucocorticoid resistance and associated with the effects of DEX + MCG were presented in Figure 7E. The gene discussed is PIK3CD; the disease is glucocorticoid resistance.