STC1 and cancer: Meanwhile, STC1 protein expression was elevated, as determined by immunohistochemistry (IHC), in liver hepatocellular carcinoma (LIHC), pancreatic adenocarcinoma (PAAD), colon adenocarcinoma (COAD), and stomach adenocarcinoma (STAD) compared to normal tissues, while it had low expression in several cancers, such as thyroid carcinoma (THCA), kidney chromophobe (KICH), and kidney renal papillary cell carcinoma (KIRP) (Figure 3d).