Examination of chromophobe and clear cell tumors from a patient with BHD revealed elevated levels of GABARAP, sequestome 1 (SQSTM1), and microtubule-associated protein 1 light chain 3 (MAP1LC3B), suggesting impaired autophagy in BHD-associated renal tumors [47]. The gene discussed is GABARAP; the disease is Birt-Hogg-Dube syndrome.