PCK1 and obesity due to melanocortin 4 receptor deficiency: A similar pattern was observed in women with upper-body obesity where the relative protein expression of PEPCK-C in omental VAT was lower than in both abdominal and femoral SAT (0.4 ± 0.0 vs. 1.2 ± 0.1 and 1.2 ± 0.1, p = 0.020 and p = 0.020, respectively) (Figure 6D).