ALB and nephrotic syndrome: Another high-risk situation is nephrotic syndrome due to membranous LN, which requires starting prophylaxis with low molecular weight heparin or vitamin K antagonists in patients with an albumin concentration < 2.5 g/dL and associated risk factors (such as proteinuria >10 g/day), and continuing it until serum albumin reaches 3.0 g/dL [239].