In the present study, we used bioinformatics tools, such as BioPortal, to analyze the clinicopathological features of ILC in the presence (CDH1-altered ILC) and absence (CDH1-unaltered ILC) of CDH1 alterations, utilizing datasets from The Cancer Genome Atlas (TCGA) and the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC). This evidence concerns the gene CDH1 and breast cancer.