In another study using an experimental model of bleomycin-induced pulmonary fibrosis in C57BL/6 mice, it was shown that the use of a vitamin D receptor agonist (paricalcitol) significantly prevented body weight loss and contributed to less pronounced fibrotic changes in lung tissue, whereas vitamin D deficiency, on the contrary, was accompanied by significantly more pronounced damage to the lung parenchyma. This evidence concerns the gene VDR and pulmonary fibrosis.