TGFB1 and adenomyosis: The overexpression of angiogenic factors, such as VEGF, annexinA2 (ANXA2), follistatin, and activin A, members of the TGF-β family, has been detected in the ectopic and eutopic endometria of patients with adenomyosis, promoting vascular sprouting and augmenting vascular permeability in angiogenesis [79,80,81].