In this regard, a synergistic antiproliferative and selective activity of the citral-doxorubicin mixture was observed on Burkitt’s lymphoma cells, which was associated with an intensification of the apoptotic stimulus (elevated levels of the pro-apoptotic protein Bak and diminished expression of the anti-apoptotic agent Bcl-xL) [25]. The gene discussed is BAK1; the disease is Burkitt lymphoma.