Although the expression of GHRH, GHRH-Rs and their SVs have previously been demonstrated in various human tumors and disorders [1,4,7,8,9,10,11,12], to the best of our knowledge there is no, or only very limited, existing information about the presence and gene expression of GHRH and its receptors and binding characteristics of GHRH-R SVs in pediatric hemato-oncological diseases, including various neoplastic conditions. The gene discussed is GHRH; the disease is neoplasm.